There is growing scientific evidence that intelligence is necessary for the development of life. This evidence is leading into the development of a new field, bio-semiotics. A growing number of biologists have realized that the laws of physics and chemistry alone cannot account for the behavior of DNA and other macro-molecules, because that same chemical composition and electrical affinities can produce many different kinds of molecules depending on the physical arrangement of the atoms in the molecule. These different physical shapes are important, as they determine what an organism is biologically. Biologist have developed models that account for semantic information in DNA that is not reducible to physical and chemical laws.